news report
Brain Immune Cells Shift Sharply From Midlife, Human Study Finds
A 40-person postmortem study found resident microglia declining from roughly ages 50 to 75, alongside stronger inflammatory signatures—but not proof of dementia causation.
topics
Brain aging
news report
NIH Study Maps a Midlife Shift in the Brain's Immune Cells
A molecular atlas of 40 healthy human hippocampi found microglia declined as inflammatory and peripheral-like immune cells became more prominent from about ages 50 to 75.